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The early years
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The story of Dipharma is closely linked with the story of its founder,
chemist and researcher Mario Biazzi (1897-1974) who, in the mid
1930’s, made significant improvements to the continuous production
process of nitroglycerin, making it much more efficient and safer.
His innovation immediately received a huge success, and plants
designed on his process were installed in several companies around
the world.
As he was perfecting his design, he felt that an experience with
production could bring significant added-value to his engineering
activities, and that is how he decided to start with some associates a
production company called “Dinamite S.p.A.” in the North-Eastern part
of Italy. Indeed, from the experiences gained there in production, he
further improved his technology to bring additional safety to the factory
workers. For example, in 1957, he designed the world’s first continuous
production plant for nitroglycerin with remote control.
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DIPHARMA
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ACQUIRED BUSINESSES
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1949-2000
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1949 Incorporation of Dinamite S.p.A.
(which later became Dipharma) for the
manufacturing of civil explosives.
1954 Mario Biazzi and Dinamite are
copromoters of SAFEX International,
an association whose aim is to
improve the safety in the explosives
industry.
1959 First automatic nitroglycerin plant on
stream at Dinamite in Mereto.
The production of nitroglycerin
was the first step into the
production of Active Pharmaceutical
Ingredients.
Indeed, since the late 1800’s the use of
nitroglycerin to treat angina and
hypertension is known.
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1962 Construction of the Caronno plant by the
company Francis (later Laporte Organics
Francis).
The same year the company SECI started
a chemical department, which later became
Secifarma. |
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1970 First FDA inspection at Secifarma.
1978 First FDA inspection at Francis. |
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1980 First FDA inspection |
1982 Acquisition of Secifarma. |
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1990 Name changes to Dinamite Dipharma to
reflect the increasing share of
pharmaceutical ingredients in the
production.
1996 New multipurpose plant for API’s and new
Biazzi hydrogenation units.
1997 Production of civil explosives discontinued
to focus entirely on API’s and
intermediates for the pharmaceutical
industry. |
1992 Incorporation of Amino Chemicals.
1996 Secifarma merged into Dinamite Dipharma.
1999 Acquisition of Amino Chemicals.
Shut down of production and start of a
three years investment program to
upgrade the facility to cGMP standards.
2000 Acquisition of Laporte Organics Francis,
name change to Dipharma Francis. |
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2000-2010
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2001
ISO-14001 environmental certification obtained for the Caronno site.
2002
First FDA inspection at Amino Chemicals.
2003
Construction of a new R&D center in Baranzate.
2004
Reached 50 cumulative patent applications.
2005
Merger of Dipharma and Dipharma Francis.
First launch of generic Fexofenadine under Paragraph IV in USA using product from Dipharma.
2006
Sales exceeded €100M for the first time.
New logo and visual identity kit.
2007
First launch of generic Pantoprazole in Austria using product from Amino Chemicals.
Amino Chemicals started a project to expand its production capacity, in order to meet an increasing portfolio of new products.
2008
Reached 100 cumulative patent applications.
2009
60 years of experience in innovation.
2010
First launch of generic Pramipexole under Paragraph IV in USA using product from Amino Chemicals.
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